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Safety Information

239488

Sigma-Aldrich

1,4-Bis(3-aminopropyl)piperazine

≥99%

Synonym(s):

1,4-(3-Aminopropyl)piperazine, 1,4-Piperazinebis(propylamine), 1,4-Piperazinedipropylamine, N,N′-Bis(γ-aminopropyl)piperazine, N,N′-Bis(3-aminopropyl)piperazine, [3-[4-(3-Aminopropyl)piperazin-1-yl]propyl]amine

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About This Item

Empirical Formula (Hill Notation):
C10H24N4
CAS Number:
7209-38-3
Molecular Weight:
200.32
EC Number:
230-589-1
MDL number:
MFCD00006161
UNSPSC Code:
12352100
PubChem Substance ID:
24854378
NACRES:
NA.22

vapor density

6.9 (vs air)

Quality Level

100

Assay

≥99%

form

liquid

refractive index

n20/D 1.502 (lit.)

bp

150-152 °C/2 mmHg (lit.)

mp

15 °C (lit.)

density

0.973 g/mL at 25 °C (lit.)

SMILES string

NCCCN1CCN(CCCN)CC1

InChI

1S/C10H24N4/c11-3-1-5-13-7-9-14(10-8-13)6-2-4-12/h1-12H2

InChI key

XUSNPFGLKGCWGN-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

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General description

The thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) were studied in aqueous solution using a potentiometric technique.

Application

1,4-Bis(3-aminopropyl)piperazine was used to functionalize natural montmorillonite (M) and synthetic kanemite (K).

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

325.4 °F - closed cup

Flash Point(C)

163 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

239488-50ML:
239488-BULK:
239488-10ML:
239488-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKBG8619V
MKBG8631V
MKBG8615V
MKBG8620V
MKBG8621V

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Ahmed A El-Sherif et al.
Bioinorganic chemistry and applications, 2012, 984291-984291 (2012-12-12)
Thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) and its metal complexation with some divalent metal ions were determined in aqueous solution at constant ionic strength (0.1 M NaNO(3)) using a potentiometric technique. The order of -ΔG(0) and -ΔH(0) was found to
Jian Cheng et al.
Acta biomaterialia, 30, 155-167 (2015-12-02)
Nano-polyplexes from bioreducible cationic polymers have a massive promise for cancer gene therapy. However, the feasibility of cationic polyurethanes for non-viral gene therapy is so far not well studied. In this work, a linear cationic polyurethane containing disulfide bonds, urethane
Romain Gautier et al.
Advanced materials (Deerfield Beach, Fla.), 31(14), e1807383-e1807383 (2019-02-19)
Hybrid metal halides containing perovskite layers have recently shown great potential for applications in solar cells and light-emitting diodes. Such compounds exhibit quantum confinement effects leading to tunable optical and electronic properties. Thus, broadband white-light emission has been observed from
Yanyan Song et al.
Molecular pharmaceutics, 11(7), 2250-2261 (2014-06-04)
A folate-decorated, disulfide-based cationic dextran conjugate having dextran as the main chain and disulfide-linked 1,4-bis(3-aminopropyl)piperazine (BAP) residues as the grafts was designed and successfully prepared as a multifunctional gene delivery vector for targeted gene delivery to ovarian cancer SKOV-3 cells

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