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Safety Information

179043

Sigma-Aldrich

Borane N,N-diethylaniline complex

Synonym(s):

(N,N-Diethylaniline)trihydroboron, Diethylphenylamine-borane, NSC 239123

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About This Item

Linear Formula:
C6H5N(C2H5)2·BH3
CAS Number:
Molecular Weight:
163.07
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

form

liquid

Quality Level

reaction suitability

reagent type: reductant

mp

−30-−27 °C (lit.)

density

0.917 g/mL at 25 °C (lit.)

SMILES string

B.CCN(CC)c1ccccc1

InChI

1S/C10H15N.BH3/c1-3-11(4-2)10-8-6-5-7-9-10;/h5-9H,3-4H2,1-2H3;1H3

InChI key

YPWBYWNNJVSNPQ-UHFFFAOYSA-N

Application

Reactant for:
  • Diastereoselective reduction of prochiral enone intermediates
  • Borylation of aryl halides
  • Reductions of ketones, acids, esters, amides, and nitriles
  • Investigations of borane source on enantioselectivity in enantiopure oxazaborolidine-catalyzed asymmetric borane reduction of ketones

Reactant for synthesis of:
  • Chromanol derivatives as CETP inhibitors for the treatment of cardiovascular disease
  • Allylic alcohols via enantioselective reductions
  • Pinacolboranes for one-pot synthesis of unsymmetrical biaryls

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2 - Water-react 2

Supplementary Hazards

Storage Class Code

4.3 - Hazardous materials which set free flammable gases upon contact with water

WGK

WGK 3

Flash Point(F)

69.8 °F - closed cup

Flash Point(C)

21 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 2 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

179043-VAR:
179043-25G:
179043-PZ:
179043-100G:
179043-1KG:
179043-BULK:


Certificates of Analysis (COA)

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