Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

159549

Sigma-Aldrich

4-(Bromomethyl)benzoic acid

97%

Synonym(s):

α-Bromo-p-toluic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrCH2C6H4CO2H
CAS Number:
6232-88-8
Molecular Weight:
215.04
Beilstein:
1862870
EC Number:
228-343-3
MDL number:
MFCD00002567
UNSPSC Code:
12352100
PubChem Substance ID:
24849820
NACRES:
NA.22

Quality Level

200

Assay

97%

form

solid

mp

224-229 °C (lit.)

functional group

bromo
carboxylic acid

SMILES string

OC(=O)c1ccc(CBr)cc1

InChI

1S/C8H7BrO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5H2,(H,10,11)

InChI key

CQQSQBRPAJSTFB-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

4-(Bromomethyl)benzoic acid was used in the chemical modification of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), second generation photosensitizer. It was also used in the synthesis of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

159549-BULK:
159549-50G:
159549-10G:
159549-VAR:
159549-5G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCG0573
BCCB9928
BCBZ9925
BCBW9397
BCBT2484

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Q Yu et al.
Chemical communications (Cambridge, England), 50(81), 12150-12153 (2014-09-02)
LiYF4:Tm(3+)/Yb(3+) upconverting nanoparticles (UCNPs) were functionalized with the second generation photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (m-THPC, Temoporfin, Foscan®). m-THPC was modified using 4-(bromomethyl)benzoic acid, which induced a bathochromic shift of the m-THPC blue absorption peak. The nanoconstruct causes up to 70% cell death
Rosanna Maccari et al.
Bioorganic & medicinal chemistry, 15(15), 5137-5149 (2007-06-05)
4-(5-Arylidene-2,4-dioxothiazolidin-3-yl)methylbenzoic acids (2) were synthesized and evaluated in vitro as inhibitors of PTP1B and LMW-PTP, two protein tyrosine phosphatases (PTPs) which act as negative regulators of the metabolic and mitotic signalling of insulin. The synthesis of compounds 2 represents an
Marcela S Lopes et al.
European journal of medicinal chemistry, 46(11), 5443-5447 (2011-09-24)
A series of nitroaromatic compounds was synthesized and evaluated as potential antileishmanial and trypanocidal agents. Five compounds exerted significant anti-leishmanial activity in vitro against promastigotes forms of Leishmania (L.) amazonensis, with IC(50) in the range of 23-59 μmol L(-1), but
Salvatore Lombardo et al.
Langmuir : the ACS journal of surfaces and colloids, 33(22), 5473-5481 (2017-05-13)
The interaction of bovine serum albumin (BSA) with sulfated, carboxylated, and pyridinium-grafted cellulose nanocrystals (CNCs) was studied as a function of the degree of substitution by determining the adsorption isotherm and by directly measuring the thermodynamics of interaction. The adsorption
Zhimei He et al.
Small (Weinheim an der Bergstrasse, Germany), 15(4), e1804131-e1804131 (2018-12-20)
During photodynamic therapy (PDT), severe hypoxia often occurs as an undesirable limitation of PDT owing to the O2 -consuming photodynamic process, compromising the effectiveness of PDT. To overcome this problem, several strategies aiming to improve tumor oxygenation are developed. Unlike
View All Related Papers

Global Trade Item Number

SKUGTIN
159549-5G4061838744654
159549-10G4061838744647
159549-50G4061832489285

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service