Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

143065

Sigma-Aldrich

3-Dimethylamino-1-propyne

97%

Synonym(s):

1-Dimethylamino-2-propyne, N,N-Dimethyl-2-propynylamine, N,N-Dimethylpropargylamine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)2NCH2C≡CH
CAS Number:
7223-38-3
Molecular Weight:
83.13
Beilstein:
1071222
EC Number:
230-620-9
MDL number:
MFCD00008575
UNSPSC Code:
12352100
PubChem Substance ID:
24848572
NACRES:
NA.22

Quality Level

100

Assay

97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

79-83 °C (lit.)

density

0.772 g/mL at 25 °C (lit.)

functional group

amine

storage temp.

2-8°C

SMILES string

CN(C)CC#C

InChI

1S/C5H9N/c1-4-5-6(2)3/h1H,5H2,2-3H3

InChI key

ILBIXZPOMJFOJP-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

3-Dimethylamino-1-propyne is a precursor for synthesis of mixed cuprate reagents.

Application

3-Dimethylamino-1-propyne was used in the synthesis of core shell systems based on noble metal nanoparticles coated by copolymers (polyacetylenes).

Biochem/physiol Actions

3-Dimethylamino-1-propyne inactivates mitochondrial monoamine oxidase from bovine liver.

Signal Word

Danger

Hazard Statements

H225,H302,H311,H314

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

17.6 °F - closed cup

Flash Point(C)

-8 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

JAN Code

143065-100G:
143065-BULK:
143065-VAR:
143065-25G:
143065-5G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCM0605
MKCJ2316
MKCB9765
MKBX1446V
MKBS5285V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A L Maycock et al.
Biochemistry, 15(1), 114-125 (1976-01-13)
3-Dimethylamino-1-propyne irreversibly inactivates mitochondrial monoamine oxidase from bovine liver. The inactivation results in the loss of absorption in the 450-500-nm region of the flavine spectrum and a concomitant increase in absorbance at 410 nm. For the enzyme-bound adduct epsilon410 =
3-(Dimethylamino)-1-propyne: convenient precursor for a versatile mixed cuprate reagent.
Ledlie DB and Miller G.
The Journal of Organic Chemistry, 44(6), 1006-1007 (1979)
John R Hoffman et al.
ACS applied materials & interfaces, 12(17), 19944-19954 (2020-04-08)
Charged functional groups are often incorporated onto the surface of nanofiltration (NF) membranes to facilitate the selective rejection of multivalent ions over monovalent ions. However, since fouling-resistant surfaces tend to be electrically neutral, the incorporation of charged functionality exacerbates membrane
Ilaria Fratoddi et al.
Nanoscale research letters, 6(1), 98-98 (2011-06-30)
Noble metal nanoparticles of different sizes and shapes combined with conjugated functional polymers give rise to advanced core shell hybrids with interesting physical characteristics and potential applications in sensors or cancer therapy. In this paper, a versatile and facile synthesis
Francesca Nunzi et al.
The journal of physical chemistry. B, 110(15), 7682-7687 (2006-04-14)
The reaction of the bifunctional organic molecule 1-(dimethylamino)-2-propyne (DMAP) on the Si(100) surface has been investigated by density functional calculations employing a two-dimer cluster model. We found that, once in the physisorbed dative bonded well (-20.0 kcal mol(-1)), DMAP can
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service