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Safety Information

13900

Sigma-Aldrich

O-Benzyl-L-serine

≥99.0% (NT)

Synonym(s):

(S)-2-Amino-3-benzyloxypropionic acid

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About This Item

Empirical Formula (Hill Notation):
C10H13NO3
CAS Number:
4726-96-9
Molecular Weight:
195.22
Beilstein:
2114846
EC Number:
225-220-6
MDL number:
MFCD00065937
UNSPSC Code:
12352200
PubChem Substance ID:
57647117
NACRES:
NA.22

Assay

≥99.0% (NT)

form

powder

optical activity

[α]20/D +21±2°, c = 2% in acetic acid: water (4:1) (+ 1 Eq HCl)

optical purity

enantiomeric ratio: ≥99.5:0.5 (TLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

~227 °C (dec.)

application(s)

peptide synthesis

SMILES string

N[C@@H](COCc1ccccc1)C(O)=O

InChI

1S/C10H13NO3/c11-9(10(12)13)7-14-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1

InChI key

IDGQXGPQOGUGIX-VIFPVBQESA-N

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

13900-25G-F:
13900-VAR-F:
13900-1G-F:
13900-BULK-F:
13900-5G-F:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR5325V
1325275
1325275V
1325275
1183329

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Sigma-Aldrich

M3262

N-Methyl-D-aspartic acid

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Pharmaceutical research, 29(1), 110-120 (2011-07-12)
To investigate the in vitro release of octreotide acetate, a somatostatin agonist, from microspheres based on a hydrophilic polyester, poly(D,L-lactide-co-hydroxymethyl glycolide) (PLHMGA). Spherical and non-porous octreotide-loaded PLHMGA microspheres (12 to 16 μm) and loading efficiency of 60-70% were prepared by a
Amir H Ghassemi et al.
Pharmaceutical research, 27(9), 2008-2017 (2010-07-06)
To study the release of a model protein, bovine serum albumin (BSA), from microspheres of an hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid) (PLHMGA). BSA-loaded microspheres were prepared by a double emulsion solvent evaporation method. The effect of copolymer composition and
Roman V Uzhachenko et al.
Cell reports, 35(1), 108944-108944 (2021-04-08)
Inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i) delay progression of metastatic breast cancer. However, complete responses are uncommon and tumors eventually relapse. Here, we show that CDK4/6i can enhance efficacy of T cell-based therapies, such as adoptive T cell transfer or
Neda Samadi et al.
Pharmaceutical research, 31(10), 2593-2604 (2014-03-15)
To investigate the effect of polyethylene glycol (PEG) in nanoparticles based on blends of hydroxylated aliphatic polyester, poly(D,L-lactic-co-glycolic-co-hydroxymethyl glycolic acid) (PLGHMGA) and PEG-PLGHMGA block copolymers on their degradation and release behavior. Protein-loaded nanoparticles were prepared with blends of varying ratios
F Kazazi-Hyseni et al.
International journal of pharmaceutics, 482(1-2), 99-109 (2014-12-17)
Poly(D,L-lactic-co-hydroxymethyl glycolic acid) (PLHMGA) is a biodegradable copolymer with potential as a novel carrier in polymeric drug delivery systems. In this study, the biocompatibility of PLHMGA microspheres (PLHMGA-ms) was investigated both in vitro in three different cell types (PK-84, HK-2

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