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138711

Sigma-Aldrich

2,4,6-Trimethoxybenzaldehyde

98%

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About This Item

Linear Formula:
(CH3O)3C6H2CHO
CAS Number:
830-79-5
Molecular Weight:
196.20
Beilstein:
1956051
EC Number:
212-598-2
MDL number:
MFCD00003313
UNSPSC Code:
12352100
PubChem Substance ID:
24848365
NACRES:
NA.22

Quality Level

100

Assay

98%

form

solid

mp

115-120 °C (lit.)

SMILES string

[H]C(=O)c1c(OC)cc(OC)cc1OC

InChI

1S/C10H12O4/c1-12-7-4-9(13-2)8(6-11)10(5-7)14-3/h4-6H,1-3H3

InChI key

CRBZVDLXAIFERF-UHFFFAOYSA-N

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General description

2,4,6-Trimethoxybenzaldehyde exhibits significant anti-candida activity.

Application

2,4,6-Trimethoxybenzaldehyde was used in the preparation and characterization of three RNA-specifc fluorescent probes (E36, E144 and F22) and their use in live cell imaging. It was used as starting reagent for the regioselective synthesis of new (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

138711-VAR:
138711-50G:
138711-BULK:
138711-10G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKBZ3019V
MKBT8374V
MKBT6021V
MKBL4588V
MKBD5633V

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3,4,5-Trihydroxybenzaldehyde monohydrate 98%

Sigma-Aldrich

259594

3,4,5-Trihydroxybenzaldehyde monohydrate

Sandeep B Rajput et al.
Chinese medicine, 8(1), 18-18 (2013-09-10)
Asaronaldehyde (2, 4, 5-trimethoxybeznaldehyde) is an active component of Acorus gramineus rhizome. This study aims to evaluate the anti-Candida efficacy of asaronaldehyde and its three structural isomers, namely, 2, 3, 4-trimethoxybenzaldehyde, 3, 4, 5-trimethoxybenzaldehyde, and 2, 4, 6- trimethoxybenzaldehyde. Susceptibility
Asma Alshamari et al.
Molecules (Basel, Switzerland), 25(18) (2020-09-24)
A series of derivatives of trans-3-(2,4,6-trimethoxyphenyl)4,5-dihydroisoxazolo-4,5-bis[carbonyl-(4'phenyl)thiosemicarbazide (9) and of trans-3-(2,4,6-trimethoxyphenyl)-4,5-dihydro isoxazolo-4,5-bis(aroylcarbohydrazide) (10a-c) were synthesized from trans-3-(2,4,6-trimethoxyphenyl)-4,5-dihydro-4,5-bis(hydrazenocarbonyl)isoxazole (8). The structures of the compounds were elucidated by both elemental and spectral (IR, NMR, and MS) analysis. Compound 9 shows activity against some
Lili Du et al.
Theranostics, 7(14), 3432-3445 (2017-09-16)
Small interfering RNA (siRNA) therapies have been hampered by lack of delivery systems in the past decades. Nowadays, a few promising vehicles for siRNA delivery have been developed and it is gradually revealed that enhancing siRNA release from endosomes into
Frederik Roelens et al.
European journal of medicinal chemistry, 40(10), 1042-1051 (2005-06-14)
Nine new (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins have been synthesized from 2,4,6-trimethoxybenzaldehyde via a short, efficient, and regioselective pathway, together with the unsubstituted analogue (+/-)-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarin. The compounds were tested for estrogenic activity using a yeast-based estrogen screen. Weak estrogenicity was determined for seven members
Fatemeh Oroojalian et al.
Journal of controlled release : official journal of the Controlled Release Society, 288, 45-61 (2018-09-02)
In the current study, thermoresponsive poly(N-isopropylacrylamide)-doxorubicin (PNIPAM-DOX) hydrogel was synthesized and loaded into pH-responsive poly ethylene glycol)-2,4,6- trimethoxy benzylidene pentaerythritol carbonate (PEG-PTMBPEC) polymersomes in order to fabricate a smart thermo-pH stimuli responsive drug delivery system. Thermo-pH responsive polymersomal formulation of
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