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Safety Information

114693

Sigma-Aldrich

1-Nitroso-2-naphthol

97%

Synonym(s):

1-Nitroso-2-hydroxynaphthalene

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About This Item

Linear Formula:
ONC10H6OH
CAS Number:
131-91-9
Molecular Weight:
173.17
Colour Index Number:
10005
Beilstein:
776947
EC Number:
205-043-0
MDL number:
MFCD00003884
UNSPSC Code:
12352100
PubChem Substance ID:
24847189
NACRES:
NA.22

Quality Level

200

Assay

97%

form

solid

mp

106-108 °C (dec.) (lit.)

functional group

C-nitroso
nitroso

SMILES string

Oc1ccc2ccccc2c1N=O

InChI

1S/C10H7NO2/c12-9-6-5-7-3-1-2-4-8(7)10(9)11-13/h1-6,12H

InChI key

YXAOOTNFFAQIPZ-UHFFFAOYSA-N

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Application

1-Nitroso-2-naphthol is the chelating ion-exchanger in the synthesis of alumina adsorbents that are of acidic, basic and neutral nature. It is used for the removal and preconcentration of Pb(II), Cu(II), Cr(III) from waste, as well as drinking water. It is also used in the preconcentration of cobalt using C(18) microcolumn with flow injection that is coupled to a flame atomic absorption spectrometry (FI-FAAS) system.
1-Nitroso-2-naphthol is used in the preparation of 1-nitroso-2-naphthol-sodium nitrite reagent.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H317,H319,H341

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

114693-5G:
114693-100G:
114693-VAR:
114693-BULK:
114693-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
STBH0889
STBG9593
STBF1603V
STBF0155V
STBD2655V

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Fluorometric measurement of tyrosine in serum and plasma.
J A Ambrose
Clinical chemistry, 20(4), 505-510 (1974-04-01)
Yingxue Ye et al.
Talanta, 57(5), 945-951 (2008-10-31)
The suitability of 1-nitroso-2-naphthol (NN) as a complexing agent for on-line preconcentration of cobalt using C(18) microcolumn with FI-FAAS system has been tested. Various parameters affecting the complex formation and its elution were optimized. Reagent solution (2.5x10(-3) mol l(-1)) and
J A Knight et al.
Clinical chemistry, 29(11), 1969-1971 (1983-11-01)
1-Nitroso-2-naphthol reacts with various 5-hydroxyindoles as well as para-substituted phenols and guaiacols. Consequently, this reaction has long been used to measure tyrosine in tyrosinosis and tyrosinemia, homovanillic acid in neuroblastoma, and 5-hydroxy-3-indoleacetic acid in the carcinoid tumor. We report here
Improved quantitation for urinary 5-hydroxyindole acetate using the nitrosonaphthol reaction.
L M Muller et al.
Clinical biochemistry, 17(1), 37-38 (1984-02-01)
A Rothstein
American journal of clinical pathology, 87(5), 644-648 (1987-05-01)
Determination of urinary homovanillic acid (HVA) is an important analysis to establish the diagnosis and prognosis of neuroblastoma. A method is presented for the determination of this metabolite of dopamine using its reaction with 1-nitroso-2-naphthol and nitrous acid. The method
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