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112704

Sigma-Aldrich

Formaldehyde-sodium bisulfite adduct

95%

Synonym(s):

Sodium formaldehyde bisulfite

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About This Item

Linear Formula:
HOCH2SO3Na
CAS Number:
870-72-4
Molecular Weight:
134.09
EC Number:
212-800-9
MDL number:
MFCD00044664
UNSPSC Code:
12352100
PubChem Substance ID:
24847109
NACRES:
NA.22

Assay

95%

form

solid

mp

200 °C (dec.) (lit.)

SMILES string

O=S(CO)([O-])=O.[Na+]

InChI

1S/CH4O4S.Na/c2-1-6(3,4)5;/h2H,1H2,(H,3,4,5);/q;+1/p-1

InChI key

UOULCEYHQNCFFH-UHFFFAOYSA-M

General description

Formaldehyde-sodium bisulfite adduct is used as a standard in the synthesis of 3-Hydroxypropionaldehyde (3HPA). It can be assayed by HPLC with fluorometric detection in selected foods.

Application


  • Triethyl citrate as a non-toxic solvent in pharmaceutical applications: Explored the use of Triethyl citrate in in-situ forming PLGA implants, focusing on its role as a less toxic solvent compared to traditional options. This application demonstrates the importance of Triethyl citrate in developing safer pharmaceutical formulations (Ramos et al., 2024).

  • Triethyl citrate in biodegradable polymer research: Examines the influence of Triethyl citrate on the melt spinning and structural properties of poly(lactic acid) fibers. This study highlights its effectiveness as a plasticizer, enhancing the processability and properties of biodegradable polymers, relevant for controlled drug release systems (Gzyra-Jagieła et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

112704-VAR:
112704-5KG:
112704-5G:
112704-100G:
112704-2KG:
112704-BULK:

Certificates of Analysis (COA)

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R Aris et al.
The American review of respiratory disease, 141(3), 546-551 (1990-03-01)
Hydroxymethanesulfonate (HMSA), the bisulfite (HSO3-) adduct of formaldehyde (CH2O), is a common constituent of California acid fogs. HMSA, most stable in a fog pH range of 3 to 5, dissociates at 6.6, the pH of the fluid lining human airways.
Yuegang Zuo
Chemosphere, 51(3), 175-179 (2003-02-20)
The determination of the photo-production rate of hydroxyl radical (OH) in atmospheric liquids is of fundamental importance to an understanding of atmospheric aquatic chemistry. Recently, several studies have been performed to examine the photo-chemical formation rate of OH in cloud
Hydroxymethylated polysulphone for islet macroencapsulation allows rapid diffusion of insulin but retains PERV.
P Petersen et al.
Transplantation proceedings, 34(1), 194-195 (2002-04-18)
C R Warner et al.
Food additives and contaminants, 7(5), 575-581 (1990-09-01)
The reaction of sulphite with formaldehyde to form hydroxymethylsulphonate (HMS), which is very stable under the controlled conditions of this assay, was used as the first step in an analytical procedure to determine foodborne sulphite. The effect of mobile-phase pH
Stephen Wai Cheung Chung et al.
Journal of AOAC International, 91(1), 98-102 (2008-04-02)
A rapid and accurate method for measuring low part-per-million levels of free and reversibly-bound sulfites in selected foods by using high-performance liquid chromatography (HPLC) with fluorometric detection was developed. Sulfites were extracted with sodium tetrachloromercurate solution and determined by HPLC-fluorescence
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