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Merck

PSMB1

proteasome (prosome, macropain) subunit, beta type, 1

Synonyms:
HC5, PMSB1, PSC5
Species:
UniProtKB ID:
Gene ID:
  • Human(5689) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
  • Mouse(19170) proteasome (prosome, macropain) subunit, beta type 1
  • Rat(94198) proteasome (prosome, macropain) subunit, beta type 1
  • Zebrafish(445413) proteasome (prosome, macropain) subunit, beta type, 1
  • domestic cat(101101060) proteasome (prosome, macropain) subunit, beta type, 1
  • dog(475040) proteasome (prosome, macropain) subunit, beta type, 1
  • chicken(421551) proteasome (prosome, macropain) subunit, beta type, 1
  • cow(514237) proteasome (prosome, macropain) subunit, beta type, 1
  • sheep(101116408) proteasome (prosome, macropain) subunit, beta type, 1
  • naked mole-rat(101701261) proteasome (prosome, macropain) subunit, beta type, 1
  • domestic guinea pig(100734982) proteasome (prosome, macropain) subunit, beta type, 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
20S Proteasome Fraction from rabbit, ≥95% (SDS-PAGE), solution,
Species

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PSMB1,
Species
human
MISSION® esiRNA, targeting mouse Psmb1,
Species
mouse