Skip to Content
Merck

CTLA4

cytotoxic T-lymphocyte-associated protein 4

Synonyms:
CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
Species:
Human CTLA4 (1493), Mouse Ctla4 (12477), Rat Ctla4 (63835), Domestic Rabbit CTLA4 (100009412), domestic guinea pig Ctla4 (100725760), naked mole-rat Ctla4 (101722788), chicken CTLA4 (424106), domestic cat CTLA4 (493743), cow CTLA4 (281732), dog CTLA4 (403696)
UniProtKB ID:
P16410, A0N1S0, E9PDH0, O95653, Q0PP65, Q52MC1, Q53TD5, Q5S005
Gene ID:
  • Human(1493) Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Mouse(12477) cytotoxic T-lymphocyte-associated protein 4
  • Rat(63835) cytotoxic T-lymphocyte-associated protein 4
  • Domestic Rabbit(100009412) cytotoxic T-lymphocyte-associated protein 4
  • domestic guinea pig(100725760) cytotoxic T-lymphocyte-associated protein 4
  • naked mole-rat(101722788) cytotoxic T-lymphocyte-associated protein 4
  • chicken(424106) cytotoxic T-lymphocyte-associated protein 4
  • domestic cat(493743) cytotoxic T-lymphocyte-associated protein 4
  • cow(281732) cytotoxic T-lymphocyte-associated protein 4
  • dog(403696) cytotoxic T-lymphocyte-associated protein 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB0109
Human CXCL16 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
RAB0110
Mouse CTLA-4 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1403712
Monoclonal Anti-CTLA4 antibody produced in mouse, clone 2F1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
MABF389
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
MABF545
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
SAB1306189
ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
MABF158C
Anti-CD152 (CTLA-4) (mouse), PE-Cy7, clone UC10-4F10-11 Antibody, clone UC10-4F10-11, from hamster(Armenian), PE-Cy7,
Species Reactivity
mouse
Application
flow cytometry

Proteins

Product Number
Description
Species
SRP8051
CD152 (human): FC (human) (non-lytic), recombinant, expressed in CHO cells, ≥98% (SDS-PAGE),
Species
human
C4483
CD152/Fc Chimera, Cytolytic from mouse, recombinant, expressed in NS.1 cells, buffered aqueous solution,
Species
mouse

esiRNA

Product Number
Description
Species
EHU124981
MISSION® esiRNA, targeting human CTLA4,
Species
human