568513-U

Discovery^® HS C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 4 mm, HPLC Column

• Sinonimo/i: Discovery RP18 HPLC Column
• Codice UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Proprietà

• Nome del prodotto: Colonna HPLC Discovery^® HS C18, 5 μm particle size, L × I.D. 25 cm × 4 mm
• Materiali: stainless steel column
• Livello qualitativo: 100
• agenzia: suitable for USP L1
• Nome Commerciale: Discovery^®
• Caratteristiche: endcapped
• Produttore/marchio commerciale: Discovery^®
• Confezionamento: 1 ea of
• Grado di funzionalizzazione: 20% Carbon loading
• Parametri: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• tecniche: HPLC: suitable; LC/MS: suitable
• Lungh. × D.I.: 25 cm × 4 mm
• Area superficiale: 300 m²/g
• Copertura della superficie: 3.2 μmol/m²
• Impurezze: <10 ppm metals
• Matrice: silica gel, high purity, spherical particle platform; fully porous particle
• Gruppo funzionale matrice: C18 (octadecyl) phase
• Dimensione particelle: 5 μm
• Dimensione pori: 120 Å
• Intervallo di pH d’impiego: 2-8
• applicazioni: food and beverages
• Tecnica di separazione: reversed phase

Descrizione

Applicazioni

• A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This research developed a robust RP-HPLC method for the quantitative analysis of molnupiravir, a COVID-19 therapeutic, utilizing nanoformulations. The study highlights the method′s stability and effectiveness in permeability studies, demonstrating its potential in pharmaceutical analysis (Reçber et al., 2022).


• Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: The study developed and validated an HPLC-UV method for analyzing terizidone in plasma, essential for pharmacokinetic studies in patients with drug-resistant tuberculosis. The method′s reliability supports its use in clinical and pharmacological research (Mulubwa and Mugabo, 2018).


• Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: This research focuses on optimizing a liquid chromatography method to quantify doxorubicin in plasma and urine. It is crucial for pharmacokinetic, biomedical, and drug monitoring studies, ensuring accurate and precise therapeutic monitoring (Maliszewska et al., 2018).


• Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV.: This study introduces a universal HPLC-UV method for determining efavirenz in various biological matrices, including transport studies, rat placenta perfusion, and lysate. It is significant for pharmacokinetic and drug distribution research (Zelena et al., 2017).

Caratteristiche e vantaggi

• Stabile, a bassa perdita per applicazioni LC-MS
• Scalabile dalla colonna analitica alla preparatoria
• Molto stabile per garantire una eccellente riproducibilità da un ciclo all′altro e da un lotto all′altro
• Maggiore idrofobia per una migliore risoluzione degli analiti difficili

   

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Note legali

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany