T0632

Sodium thioglycolate

≥96.5% (iodometric)

• Sinonimo/i: Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt
• Formula condensata: HSCH₂COONa
• Numero CAS: 367-51-1
• Peso molecolare: 114.10
• Beilstein: 4569109
• Numero CE: 206-696-4
• Numero MDL: MFCD00043386
• Codice UNSPSC: 12352201
• ID PubChem: 24899901
• NACRES: NA.25

Proprietà

• Saggio: ≥96.5% (iodometric)
• Stato: powder
• Colore: white to off-white
• Intervallo di pH utile: 6.7 (20 °C, 100 g/L)
• Punto di fusione: >300 °C (lit.)
• Solubilità: water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Na+].[O-]C(=O)CS
• InChI: 1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1; GNBVPFITFYNRCN-UHFFFAOYSA-M

Descrizione

Applicazioni

Sodium thioglycolate has been used:

• as a growth supplement in enrichment media and to study its effect on Arcobacter
• in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
• in electron microscopy

Azioni biochim/fisiol

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Avvertenza

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H290,H301,H312,H317,H412
• Consigli di prudenza: P234 - P261 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves