SRP5182

FRS3, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Sinonimo/i: FRS2β, FRS2B, MGC17167, SNT2
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Ricombinante: expressed in baculovirus infected Sf9 cells
• Saggio: ≥70% (SDS-PAGE)
• Forma fisica: buffered aqueous glycerol solution
• PM: ~87 kDa
• N° accesso NCBI: NM_006653
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: human ... FRS3(10817)

Descrizione

Descrizione generale

FRS3 or fibroblast growth factor receptor substrate 3 is a peripheral plasma membrane protein that is a substrate for the fibroblast growth factor receptor. During FGF or NGF stimulation, FRS3 becomes tyrosine phosphorylated and then serves as a platform for the recruitment of multiple signaling proteins for activation of the Ras-MAP kinase signaling cascade. FRS3 is mainly expressed in fibroblast and myoblast cell lines and undergo robust tyrosine phosphorylation in response to several mitogenic ligands. Through interaction with Rho family of small GTPases, FRS3 has been implicated in the reorganization of the actin cytoskeleton and subsequent morphological changes in various cells.

Stato fisico

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Nota sulla preparazione

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable