SMB01061

Emetine

≥90% (LC/MS-ELSD)

• Sinonimo/i: (-)-Emetine
• Formula empirica (notazione di Hill): C₂₉H₄₀N₂O₄
• Numero CAS: 483-18-1
• Peso molecolare: 480.64
• Numero MDL: MFCD00242944
• Codice UNSPSC: 12352205
• NACRES: NA.25

Proprietà

• Origine biologica: plant
• Saggio: ≥90% (LC/MS-ELSD)
• Stato: solid
• PM: 480.64
• Solubilità: water: soluble
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: N21[C@@H](C[C@@H]([C@H](C2)CC)C[C@H]4NCCc5c4cc(c(c5)OC)OC)c3c(cc(c(c3)OC)OC)CC1
• InChI: 1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1; AUVVAXYIELKVAI-CKBKHPSWSA-N

Descrizione

Descrizione generale

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Applicazioni

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Azioni biochim/fisiol

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.

Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Caratteristiche e vantaggi

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable