SCP0132
Endomorphin I
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About This Item
Formula empirica (notazione di Hill):
C34H38N6O5
Peso molecolare:
610.70
Codice UNSPSC:
12352200
NACRES:
NA.32
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Saggio
≥95% (HPLC)
Forma fisica
lyophilized
Composizione
Peptide Content, ≥77%
Condizioni di stoccaggio
protect from light
Temperatura di conservazione
−20°C
Amino Acid Sequence
Tyr-Pro-Trp-Phe-NH2
Applicazioni
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2, YPWF-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2, YPFF-NH2) are endogeneous opioid tetrapeptides with high affinity and specificity for the μ (mu) opioid receptor. Endomorphin-1 and 2 may be used to study the differential action and metabolism of these opioids.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
The opioid peptide dynorphin suppresses pituitary-ovary axis in the tilapia Oreochromis mossambicus.
Vijayalaxmi et al.
Journal of fish biology, 96(3), 747-754 (2020-02-01)
The opioid peptides are involved in the regulation of neuroendocrine functions in vertebrates. Nonetheless, the influence of an opioid peptide, dynorphin A (DYN), on reproduction in fish is understudied. The aim of this work was to study the influence of
Yoshio Okada et al.
Vitamins and hormones, 65, 257-279 (2002-12-17)
Opioid peptides and their G-protein-coupled receptors (delta, kappa, mu) are located in the central nervous system and peripheral tissues. The opioid system has been studied to determine the intrinsic mechanism of modulation of pain and to develop uniquely effective pain-control
Jakub Fichna et al.
Pharmacological reviews, 59(1), 88-123 (2007-03-03)
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2) are two endogenous opioid peptides with high affinity and remarkable selectivity for the mu-opioid receptor. The neuroanatomical distribution of endomorphins reflects their potential endogenous role in many major physiological processes, which include perception of pain
Anna Janecka et al.
Peptides, 29(11), 2066-2073 (2008-08-23)
Centrally acting plant opiates, such as morphine, are the most frequently used analgesics for the relief of severe pain, even though their undesired side effects are serious limitation to their usefulness. The search for new therapeutics that could replace morphine
Megumi Shimoyama et al.
Pharmacology, 89(3-4), 145-148 (2012-03-15)
Multiple opioid receptor (OR) types and endogenous opioid peptides exist in the spinal dorsal horn and there may be interactions among these receptor types that involve opioid peptides. In a previous study we observed that antinociceptive effects of the selective
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