SAB5701744

Anti-Phospho-STAT4-Y693 antibody produced in rabbit

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: liquid
• Reattività contro le specie: human, rat, mouse
• Concentrazione: 0.976 mg/mL
• tecniche: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• N° accesso UniProt: Q14765
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr693)
• Informazioni sul gene: human ... STAT4(6775)

Descrizione

Descrizione generale

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Immunogeno

A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4

Stato fisico

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable