SAB5500187

Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP141, affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Ricombinante: expressed in proprietary host
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: SP141, monoclonal
• Reattività contro le specie: human (tested)
• Reattività contro le specie (prevista in base all’omologia): rat, mouse
• tecniche: flow cytometry: 1:100; immunohistochemistry: 1:100
• Isotipo: IgG
• N° accesso UniProt: P43699
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... NKX2-1(7080)

Descrizione

Descrizione generale

Thyroid transcription factor-1 (TTF-1), also known as NK2 homeobox 1(NKX2-1), is a member of the NKx2 family of homeodomain transcription factors. It binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is expressed in epithelial cells of the thyroid gland and the lung, and their derived tumors such as lung adenocarcinoma and small cell carcinomas and thyroid cancer. It is absent in mesotheliomas, breast cancer, and colon cancer.

Immunogeno

Synthetic peptide derived from the internal region of human TTF-1 protein.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable