SAB5200921

Monoclonal Anti-Notch1 - Percp antibody produced in mouse

clone S253-32, purified immunoglobulin

• Sinonimo/i: Anti-Motch, Anti-Neurogenic locus notch homolog protein 1, Anti-Neurogenic locus notch protein homolog, Anti-TAN1
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: Peridinin-Chlorophyll-Protein Complex
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: S253-32, monoclonal
• Forma fisica: buffered aqueous solution
• PM: antigen predicted mol wt >270, ~120 kDa
• Reattività contro le specie: mouse, rat, human
• Concentrazione: 1 mg/mL
• tecniche: immunocytochemistry: suitable; western blot: suitable
• Isotipo: IgG1
• N° accesso NCBI: NP_032740.3
• N° accesso UniProt: Q07008
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Notch1(18128)

Descrizione

Descrizione generale

The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.

Immunogeno

Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1

Azioni biochim/fisiol

The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable