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Merck
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Documenti fondamentali

SAB4700189

Sigma-Aldrich

Monoclonal Anti-CD44-FITC antibody produced in rat

clone IM7, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Anti-Pgp-1

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.44

Origine biologica

rat

Coniugato

FITC conjugate

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

IM7, monoclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

mouse, human, canine

Concentrazione

0.5 mg/mL

tecniche

flow cytometry: suitable

Isotipo

IgG2b

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CD44(960)

Descrizione generale

The rat monoclonal antibody IM7 reacts with CD44 antigen (Phagocyte glycoprotein 1), an 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. The antibody reacts with all isoforms of mouse CD44.

Immunogeno

Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1

Applicazioni

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Venkatesh L Hegde et al.
Journal of leukocyte biology, 84(1), 134-142 (2008-04-05)
CD44 is involved in several biological processes owing to its dual role as a cell adhesion and signaling molecule. In an allogeneic dendritic cell (DC)-T cell interaction model, we show here that CD44 gets clustered at the contact between T
Jiayan Guo et al.
Molecular medicine reports, 16(4), 4095-4100 (2017-07-22)
Minimally invasive aesthetic and cosmetic procedures have increased in popularity. Injectable dermal fillers provide soft tissue augmentation, improve facial rejuvenation and wrinkles, and correct tissue defects. To investigate the use of adipose‑derived stem cells integrated with a hyaluronic acid based
Guodong Xiao et al.
Oncotarget, 8(61), 103261-103273 (2017-12-22)
Stem-like cells in tumor group featured the major role in the chemotherapy resistance of breast cancer, and the reduction of stem-like cells helped to perish the tumor when receiving chemotherapy. Smaller stem cells number indicated better therapeutic effect in vitro

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