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CdO/CdA

SAB4700079

Monoclonal Anti-CD7 antibody produced in mouse

Name: Monoclonal Anti-CD7 antibody produced in mouse
Brand: SIGMA

clone MEM-186, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Anti-GP40

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About This Item

Codice UNSPSC:

12352203

NACRES:

NA.41

Origine biologica

mouse

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

MEM-186, monoclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Concentrazione

1 mg/mL

tecniche

flow cytometry: suitable

Isotipo

IgG1

N° accesso NCBI

NM_006137.6

N° accesso UniProt

P09564

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Informazioni sul gene

human ... CD7(924)

Descrizione generale

The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Immunogeno

Human acute myelogenous leukaemia cell line KG-1

Applicazioni

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Untreated stage IV melanoma patients exhibit abnormal monocyte phenotypes and decreased functional capacity.

Rahul Chavan et al.

Cancer immunology research, 2(3), 241-248 (2014-04-30)

Monocytes may contribute to tumor progression in part by mediating tumor-induced immunosuppression. Alterations to the monocyte populations and functions in untreated patients with late-stage melanoma are not fully understood. To characterize these alterations, we compared the frequency, phenotype, and functional

9-O-acetylated sialic acids differentiating normal haematopoietic precursors from leukemic stem cells with high aldehyde dehydrogenase activity in children with acute lymphoblastic leukaemia.

Suchandra Chowdhury et al.

Glycoconjugate journal, 31(6-7), 523-535 (2014-10-07)

Childhood acute lymphoblastic leukaemia (ALL) originates from mutations in haematopoietic progenitor cells (HPCs). For high-risk patients, treated with intensified post-remission chemotherapy, haematopoietic stem cell (HSC) transplantation is considered. Autologous HSC transplantation needs improvisation till date. Previous studies established enhanced disease-associated

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