Passa al contenuto
Merck
Tutte le immagini(2)

Key Documents

SAB4503227

Sigma-Aldrich

Anti-OR51E2 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, Prostate-specific G-protein coupled receptor

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 35 kDa

Reattività contro le specie

rat, human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

N° accesso NCBI

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... O51E2(81285)

Categorie correlate

Descrizione generale

Anti-OR51E2 Antibody detects endogenous levels of total OR51E2 protein.

OR51E2 (olfactory receptor family 51 subfamily E member 2),also known as PSGR, codes for a G-protein–coupled receptor. It is a member of the odorant receptors family. OR51E2 is present in early endosomes. It is mapped to human chromosome 11p15.

Immunogeno

The antiserum was produced against synthesized peptide derived from human OR51E2.

Immunogen Range: 221-270

Azioni biochim/fisiol

OR51E2 (olfactory receptor family 51 subfamily E member 2) helps to mediate rapid, non-genomic, steroidal signaling in prostate cancer cells. It also promotes the growth of early prostate cancer.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
Gelis L, et al.
The Journal of Biological Chemistry, 291(34), 17772-17786 (2016)
Lian Gelis et al.
Experimental dermatology, 26(7), 569-576 (2017-02-14)
We identified the olfactory receptor 51E2 in human melanoma and have measured both OR51E2 mRNA and protein expression in melanoma tissue sections. qPCR analysis revealed that the receptor is upregulated in melanoma cells compared to normal melanocytes, indicating that OR51E2
The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical-genomic driver associations
Lee H, et al.
Genome Medicine, 7(1), 112-112 (2015)
Nikolina Jovancevic et al.
Frontiers in physiology, 8, 888-888 (2017-12-19)
The odorant receptor 51E2 (OR51E2), which is well-characterized in prostate cancer cells and epidermal pigment cells, was identified for the first time as the most highly expressed OR in human fetal and adult retinal pigment epithelial (RPE) cells. Immunofluorescence staining
Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers
Weng J, et al.
International Journal of Cancer. Journal International Du Cancer, 113(5), 811-818 (2005)

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.