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Key Documents

SAB4502489

Sigma-Aldrich

Anti-Parathyroid Hormone antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

PTH/PTHr receptor, PTH/PTHrP type I receptor, PTHR1, Parathyroid hormone/parathyroid hormone-related peptide receptor precursor

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 12 kDa

Reattività contro le specie

human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
western blot: 1:500-1:1000

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... PTH(5741)

Descrizione generale

Anti-Parathyroid Hormone antibody detects endogenous levels of total parathyroid hormone protein.
The PTH (parathyroid hormone) gene is mapped to human chromosome 11p15.3.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone.

Immunogen Range: 51-100

Azioni biochim/fisiol

PTH (parathyroid hormone) significantly maintains calcium and phosphate homeostasis. The function of PTH is brought about by PTH receptor, a G protein-coupled receptor. Upregulation of PTH is observed in hyperparathyroidism, which leads to hypertension, bone and cardiovascular disease. PTH is also known to improve fracture healing.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Parathyroid pathology: hyperparathyroidism and parathyroid tumors.
Carlson D
Archives of Pathology & Laboratory Medicine, 134(11), 1639-1644 (2010)
Effects of parathyroid hormone 1-34 on osteogenic and chondrogenic differentiation of human fracture haematoma-derived cells in vitro.
Dogaki Y
Journal of Tissue Engineering and Regenerative Medicine, 10(10), E365-E371 (2016)
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.
Sneddon WB
The Journal of Biological Chemistry, 291(36), 18632-18642 (2016)
Genetic Variants Associated with Circulating Parathyroid Hormone.
Robinson-Cohen C
Journal of the American Society of Nephrology, 28(5), 1553-1565 (2017)
N Demirkan et al.
International journal of immunopathology and pharmacology, 27(2), 253-260 (2014-07-10)
The aim of this study is to investigate the histopathological findings of drill hole healing and interactions of parathyroid hormone (PTH), β-catenin and transcription factor-4 (TCF7L2/Tcf-4) after local application of recombinant human bone morphogenic protein-2 (rhBMP-2). Sprague Dawley rats were

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