SAB4501074

Anti-GAD1 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: 67 kDa glutamic acid decarboxylase, GAD-67, GAD1, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 66 kDa
• Reattività contro le specie: mouse, human, rat
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: Q99259
• N° accesso UniProt: Q99259
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... GAD1(2571)

Descrizione

Descrizione generale

Anti-GAD1 antibody detects endogenous levels of total GAD1 protein.

GAD1 gene (glutamate decarboxylase 1) codes for a glutamic acid decarboxylase enzyme (GAD67), that is of 67 kDa. It is mapped to human chromosome 2q31.1.

Immunogeno

The antiserum was produced against synthesized peptide derived from human GAD1.

Immunogen Range: 471-520

Azioni biochim/fisiol

GAD1 gene (glutamate decarboxylase 1) participates in GABA (γ-aminobutyric acid) synthesis. Variations in GAD1 results in hyperactivity in attention-deficit/hyperactivity disorder. It is also characterized with childhood-onset schizophrenia and cortical gray matter volume loss.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable