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Key Documents

SAB4300599

Sigma-Aldrich

Anti-MET (Ab-1003) antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

Anti-AUTS9 antibody produced in rabbit, Anti-HGFR antibody produced in rabbit, Anti-RCCP2 antibody produced in rabbit, Anti-c-Met antibody produced in rabbit, Anti-met proto-oncogene (hepatocyte growth factor receptor) antibody produced in rabbit

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

~156 kDa

Reattività contro le specie

rat, human, mouse

Concentrazione

1 mg/mL

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

Isotipo

IgG

Sequenza immunogenica

(V-D-Y-R-A)

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... MET(4233)

Descrizione generale

MET/c-Met (mesenchymal-epithelial transition factor) is a tyrosine kinase receptor , that is located on chromosome 7q31.

Immunogeno

Peptide sequence around aa. 1001-1005 (V-D-Y-R-A), according to the protein MET.

Azioni biochim/fisiol

MET/c-Met (mesenchymal-epithelial transition factor) controls several biological processes like cell scattering, survival, proliferation, migration and c-MET signaling.(31)

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrizione del bersaglio

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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The c-Met receptor: Implication for targeted therapies in colorectal cancer
Safaie Qamsari E, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(5) (2017)
Nayeon Lee et al.
Biochemistry and biophysics reports, 26, 100973-100973 (2021-03-16)
Hepatocyte growth factor (HGF) is a neurotrophic factor and its role in peripheral nerves has been relatively unknown. In this study, biological functions of HGF and its receptor c-met have been investigated in the context of regeneration of damaged peripheral
Kyeong Ryang Ko et al.
Scientific reports, 8(1), 8316-8316 (2018-05-31)
During the peripheral nerve regeneration process, a variety of neurotrophic factors play roles in nerve repair by acting on neuronal or non-neuronal cells. In this report, we investigated the role(s) of hepatocyte growth factor (HGF) and its receptor, c-met, in
Phase II study of the c-MET inhibitor tivantinib (ARQ 197) in patients with relapsed or relapsed/refractory multiple myeloma
Baljevic M, et al.
Annals of Hematology, 96(6), 977-985 (2017)
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
Choueiri TK, et al.
Journal of Clinical Oncology, 31(2), 181-186 (2013)

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