SAB4300282

Anti-phospho-SYK (pTyr³²³) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-DKFZp313N1010 antibody produced in rabbit, Anti-FLJ25043 antibody produced in rabbit, Anti-FLJ37489 antibody produced in rabbit, Anti-spleen tyrosine kinase antibody produced in rabbit
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~72 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: 1 mg/mL
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (N-P-YP-E-P)
• N° accesso NCBI: NP_001128524.1
• N° accesso UniProt: P43405
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr323)
• Informazioni sul gene: human ... SYK(6850)

Descrizione

Descrizione generale

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. The gene encoding it is localized on human chromosome 9q22.

Immunogeno

Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P), according to the protein SYK.

Azioni biochim/fisiol

Spleen tyrosine kinase (SYK) is a tumor suppressor gene that helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. The protein helps to phosphorylate the α-tubulin subunits of microtubules. SYK aids in the coupling of receptors for antigen-antibody complexes. It also modulates cell proliferation and differentiation.

Caratteristiche e vantaggi

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Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable