SAB4300047

Anti-phospho-PTK2 (pTyr⁸⁶¹) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-FADK antibody produced in rabbit, Anti-FAK antibody produced in rabbit, Anti-FAK1 antibody produced in rabbit, Anti-PTK2 protein tyrosine kinase 2 antibody produced in rabbit, Anti-pp125FAK antibody produced in rabbit
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~125 kDa
• Reattività contro le specie: human
• Concentrazione: 1 mg/mL
• tecniche: western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (H-I-YP-Q-P)
• N° accesso NCBI: NP_005598.3
• N° accesso UniProt: Q05397
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr861)
• Informazioni sul gene: human ... PTK2(5747)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P), according to the protein PTK2.

Caratteristiche e vantaggi

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Descrizione del bersaglio

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable