SAB2900334

Anti-HSP90AA1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: heat shock protein hsp 90-alpha, hsp 86, hsp90a, hspc1, hspca
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• Reattività contro le specie: human, rat, mouse, chicken, monkey, Drosophila
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; indirect ELISA: suitable; western blot: suitable
• N° accesso UniProt: P07900
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... HSP90AA1(3320)

Descrizione

Descrizione generale

Heat shock protein 90 (Hsp90α) gene is mapped to human chromosome 14q32.31. Hsp90α is an isoform of Hsp90 and is a cytoplasmic protein that comprises three domains, namely C-terminal, middle domain, and N-terminal nucleotide-binding domain. This protein is associated with membrane microdomains and lipid rafts.

Immunogeno

Synthetic peptide from human HSP90AA1 / Hsp90.

Applicazioni

Anti-HSP90AA1 antibody produced in rabbit has been used in immunohistochemistry at a dilution of 1:400.

Azioni biochim/fisiol

Heat shock protein 90 alpha family class A member 1 (HSP90AA1 or Hsp90α) is upregulated during stress and helps in survival from membrane stress, especially during drug targeting. It elicits cytoprotective function and mediates protein homeostasis in the cytoplasm. An elevated level of Hsp90α is observed during chronic obstructive pulmonary disease (COPD). Hsp90α also favors spermatocyte maturation and human ether-a-go-go-related gene (hERG) ion channel maturation.

Caratteristiche e vantaggi

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Stato fisico

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable