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Merck
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Documenti fondamentali

SAB2500321

Sigma-Aldrich

Anti-DNMT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-CXXC9, Anti-DNA (cytosine-5-)-methyltransferase 1, Anti-DNMT, Anti-FLJ16293, Anti-MCMT

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About This Item

Numero MDL:
MFCD06201933
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

goat

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

Reattività contro le specie

pig, mouse, bovine, canine, human, rat

tecniche

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

N° accesso UniProt

P26358

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... DNMT1(1786)

Categorie correlate

Immunogeno

Peptide with sequence C-RFESPPKTQPTEDN from the internal egion of the protein sequence according to NP_001370.1 .

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319

Consigli di prudenza

P305 + P351 + P338

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
8317P1

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Umashanker Navik et al.
Molecular nutrition & food research, 63(23), e1801401-e1801401 (2019-09-19)
The aim of the current study is to evaluate whether l-methionine supplementation (l-Met-S) improves type 2 diabetes-induced alterations in glucose and lipid metabolism by modulating one-carbon metabolism and methylation status. Diabetes is induced in male Sprague-Dawley rats using high-fat diet
Mina Sasaki et al.
Biochemical and biophysical research communications, 452(3), 622-628 (2014-09-03)
Reactive oxygen species (ROS) can cause severe damage to DNA, proteins and lipids in normal cells, contributing to carcinogenesis and various pathological conditions. While cellular senescence arrests the early phase of cell cycle without any detectable telomere loss or dysfunction.
Ming Li et al.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 26(4), 371-381 (2014-09-19)
To better understand the contribution of dysregulated DNA methyltransferase 1 (DNMT1) expression to the progression and biology of clear cell renal cell carcinoma (ccRCC). We examined the differences in the expression of DNMT1 in 89 ccRCC and 22 normal tissue
Vanesa G Martinez et al.
Cellular & molecular immunology, 11(4), 343-354 (2014-03-04)
Apoptosis inhibitor of macrophages (AIMs), a homologue of human Spα, is a mouse soluble member of the scavenger receptor cysteine-rich superfamily (SRCR-SF). This family integrates a group of proteins expressed by innate and adaptive immune cells for which no unifying
Bo Ra You et al.
Molecular carcinogenesis, 53(11), 847-857 (2013-05-11)
Zebularine (Zeb) is a DNA methyltransferase (DNMT) inhibitor to that has an anti-tumor effect. Here, we evaluated the anti-growth effect of Zeb on A549 lung cancer cells in relation to reactive oxygen species (ROS) levels. Zeb inhibited the growth of

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