S8689

Fas Ligand, soluble human

recombinant, expressed in HEK 293 cells, lyophilized powder

• Sinonimo/i: SuperFas Ligand^™
• Numero MDL: MFCD01092558
• Codice UNSPSC: 12352202
• NACRES: NA.56

Proprietà

• Origine biologica: human
• Livello qualitativo: 200
• Ricombinante: expressed in HEK 293 cells
• Saggio: ≥95% (SDS-GE)
• Stato: lyophilized powder
• PM: 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions); 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)
• tecniche: ligand binding assay: suitable
• N° accesso UniProt: P48023
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... FASLG(356)

Descrizione

Applicazioni

ED₅₀ = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFas Ligand^™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

Azioni biochim/fisiol

Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.

Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).

Note legali

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable