S7796

Sisomicin sulfate salt

≥580 μg/mg (USP)

• Sinonimo/i: O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1->6))-2-deoxy-L-streptamine sulfate (2:5) (salt)
• Formula empirica (notazione di Hill): C₁₉H₃₇N₅O₇ · 2.5H₂O₄S
• Numero CAS: 53179-09-2
• Peso molecolare: 692.72
• Numero CE: 258-414-4
• Codice UNSPSC: 51281665
• ID PubChem: 329824589
• NACRES: NA.85

Proprietà

• Stato: powder
• Concentrazione: ≥580 μg/mg (USP)
• Colore: white to off-white
• Spettro attività antibiotica: Gram-negative bacteria
• Modalità d’azione: protein synthesis | interferes
• Temperatura di conservazione: −20°C
• Stringa SMILE: OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(CN)=CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6OC(CN)=CC[C@H]6N)[C@@H]5O
• InChI: 1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+;;;;;/m11...../s1; CIKNYWFPGZCHDL-ZHFUJENKSA-N

Descrizione

Descrizione generale

Chemical structure: aminoglycoside

Applicazioni

Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva . It is used in disk and tube dilution sensitivity test.

Azioni biochim/fisiol

Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus.

Confezionamento

250MG,1G,5G

Stoccaggio e stabilità

Keep container tightly closed in a dry and well-ventilated place.

Altre note

Keep container tightly closed in a dry and well-ventilated place.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H312 + H332,H360
• Consigli di prudenza: P202 - P261 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges