RAB0219
Human sICAM1 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
Prodotti consigliati
Reattività contro le specie
human
Confezionamento
kit of 96 wells (12 strips x 8 wells)
tecniche
ELISA: suitable
capture ELISA: suitable
input
sample type urine
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 150 pg/mL
standard curve range: 0.313-20 ng/mL
Metodo di rivelazione
colorimetric
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... ICAM1(3383)
Descrizione generale
The Human sICAM-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human soluble ICAM-1 in serum, plasma, cell culture supernatants and urine.
Immunogeno
Recombinant Human ICAM1
Applicazioni
For research use only. Not for use in diagnostic procedures.
Human sICAM1 (intercellular adhesion molecule 1) ELISA Kit has been used for measuring sICAM1 levels in the endothelial cell-conditioned medium.
Human sICAM1 (intercellular adhesion molecule 1) ELISA Kit has been used for measuring sICAM1 levels in the endothelial cell-conditioned medium.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Azioni biochim/fisiol
The expression of ICAM1 (intercellular adhesion molecule 1) is strongly increased by Interleukin-1 (IL-1) and interferon (IFN)-γ. It is expressed on lymphoid cells where it is required for phorbol ester-induced aggregation. It participates in LFA-1-dependent NK cell stimulation through its attachment to actin cytoskeleton through α-actinin or ezrin. It also acts as the receptor for rhinovirus, a common cold virus, and Plasmodium falciparum. Soluble ICAM-1 (sICAM1) levels are elevated in pregnant women with gestational diabetes mellitus (GDM), which is an outcome of endothelial cell activation and dysfunction. In addition, ICAM-1 also has an essential role in binding circulating leukocytes to the blood vessel wall and trans-endothelial migration to vascular intima. Meta-analysis of case-control studies show that rs1799969 polymorphism in ICAM-1 gene is linked with increased susceptibility to cancer. sICAM1 might act as a biomarker for unipolar and bipolar patients.
Altre note
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
I componenti del kit sono disponibili anche separatamente
N° Catalogo
Descrizione
SDS
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Met. Corr. 1
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Intercellular Adhesion Molecule and Endogenous NOS Inhibitor: Asymmetric Dimethylarginine in Pregnant Women with Gestational Diabetes Mellitus.
Journal of Diabetes Research, 2016:1342643 (2016)
The ICAM-1 Gly241Arg Polymorphism is Not Associated With Polycystic Ovary Syndrome - Results from a Case Control study in Kashmir, India.
Asian Pacific Journal of Cancer Prevention, 17(3), 1583-1588 (2016)
Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway.
Autophagy, 9(12), 2033-2045 (2013)
ICAM-1: getting a grip on leukocyte adhesion.
Journal of Immunology, 186(9), 5021-5023 (2011)
Soluble Intracellular Adhesion Molecule-1 in Patients with Unipolar or Bipolar Affective Disorders: Results from a Pilot Trial.
Neuropsychobiology, 74(1), 8-14 (2016)
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