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RAB0135

Sigma-Aldrich

Human NAP-2 / CXCL7 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.5 pg/mL
standard curve range: 4.1-1000 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... PPBP(5473)

Descrizione generale

Platelet-derived chemokine (C-X-C motif) ligand 7 (CXCL7), also known as neutrophil-activating protein-2 (NAP-2), is a member of a subset of seven chemokines. The protein is produced in platelets and its structure contains an N-terminal glutamate-leucine-arginine (ELR) motif. It acts as a ligand for the CXC chemokine receptor 2 (CXCR2). NAP-2 facilitates the migration of bone marrow mesenchymal stem cells (MSCs) to the injury site. In addition, it also aids in monocyte recruitment during atherogenesis. The Human NAP-2 enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants, and urine.
The Human NAP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants and urine.

Immunogeno

Recombinant Human NAP2

Applicazioni

Human NAP-2 / CXCL7 ELISA Kit has been used in enzyme-linked immunosorbent assay to quantitatively measure NAP-2/CXCL7 in serum samples of chronic myelomonocytic leukemia (CMML) patients.

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
For research use only. Not for use in diagnostic procedures.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion
GHS05

Avvertenze

Warning

Indicazioni di pericolo

H290

Consigli di prudenza

P234 - P390

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

EU REACH Annex XVII (Restriction List)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
1117I0176
0901I0176
0612F0176
0619F0176
1231F0176

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Qian Guo et al.
Oncology reports, 37(2), 1114-1122 (2016-12-14)
CXCL7 is an important chemoattractant cytokine, which signals through binding to its receptor CXCR2. Recent studies have demonstrated that the CXCL7/CXCR2 signaling plays a promoting role in several common malignancies, including lung, renal, colon, and breast cancer. However, the regulatory
Catarina R Almeida et al.
Stem cell reports, 6(4), 466-473 (2016-04-08)
Strategies for improved homing of mesenchymal stem cells (MSCs) to a place of injury are being sought and it has been shown that natural killer (NK) cells can stimulate MSC recruitment. Here, we studied the chemokines behind this recruitment. Assays
Thomas Baltus et al.
Journal of leukocyte biology, 78(2), 435-441 (2005-05-19)
Platelet-derived chemokines, such as regulated on activation, normal T expressed and secreted (RANTES; CC chemokine ligand 5), platelet factor 4 [PF4; CXC chemokine ligand 4 (CXCL4)], and epithelial neutrophil-activating protein 78 (ENA-78; CXCL5), or precursors, such as beta-thromboglobulin, which can
Wei Jiang et al.
Experimental and therapeutic medicine, 19(4), 2449-2456 (2020-04-08)
Overuse and misuse of antibiotics leads to antibiotic resistance which has become a significant public health concern. Klebsiella pneumoniae is the most common pathogenic bacteria underlying nosocomial infections due to the expression of virulence factors and occurrence of antibiotic resistance.
Kristen Meldi et al.
The Journal of clinical investigation, 125(5), 1857-1872 (2015-03-31)
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in genes encoding epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but response is highly variable, with few means to predict

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