PLA0264

Rabbit anti-Ku80 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Sinonimo/i: 80kDa, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, KARP-1, KARP1, KU80, KUB2, Ku autoantigen, Ku86, NFIV, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5, double-strand-break rejoining, lupus Ku autoantigen protein p86, nuclear factor IV, thyroid-lupus autoantigen
• Codice UNSPSC: 12352203
• NACRES: NA.41
• Reattività contro le specie: human
• application: IHC; IP; WB
• tecniche: immunohistochemistry: 1:100- 1:500; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• citations: 1

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Grado: Powered by Bethyl Laboratories, Inc.
• Reattività contro le specie: human
• tecniche: immunohistochemistry: 1:100- 1:500; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• Numero d’accesso: NP_066964.1
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: rabbit ... Ku80(7520)

Descrizione

Immunogeno

The epitope recognized by PLA0264 maps to a region between residue 150 and 200 of human Lupus Ku autoantigen protein p86 using the numbering given in entry NP_066964.1 (GeneID 7520).

Stato fisico

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Altre note

Ku80 is the 80 kDa subunit of the lupus Ku autoantigen. The lupus Ku autoantigen was identified in individuals with systemic lupus erythematosus (SLE) and related disorders. The Ku antigen is a heterodimer of Ku70 and Ku80. The Ku70/Ku80 complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P13010].

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable