PLA0013

Rabbit anti-ROCK2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Sinonimo/i: ROCK-II, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, coiled-coil-containing protein kinase II, p164 ROCK-2, rho-associated
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Grado: Powered by Bethyl Laboratories, Inc.
• Reattività contro le specie: human
• tecniche: immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:10,000-1:25,000
• Numero d’accesso: NP_004841.1
• N° accesso UniProt: O75116
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: rabbit ... ROCK2(9475)

Descrizione

Immunogeno

The epitope recognized by PLA0013 maps to a region between residues 1320 and the C-terminus (residues 1388) of human ROCK2 using the number given in entry NP_004841.1 (GeneID 9475)

Stato fisico

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Altre note

Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable