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P8791

Sigma-Aldrich

Polyglycine

mol wt 500-5,000

Sinonimo/i:

Glycine homopolymer

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About This Item

Numero CAS:
25718-94-9
Numero MDL:
MFCD00166375
Codice UNSPSC:
12352202
eCl@ss:
32160406
ID PubChem:
24898980
NACRES:
NA.26

Forma fisica

lyophilized powder

Livello qualitativo

200

PM

500-5,000

Colore

white to light yellow

Punto di fusione

300 °C

Temperatura di conservazione

−20°C

Stringa SMILE

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
DHMQDGOQFOQNFH-UHFFFAOYSA-N

Informazioni sul gene

rat ... Grin2a(24409)

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Categorie correlate

Applicazioni

Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies.

Azioni biochim/fisiol

Polyglycine exists in two forms, namely the polyglycine I (PGI) with anti-parallel β-sheet structure and polyglycine II (PGII) with extended 31-helix. It is a most flexible polypeptide with minimal steric hindrance and its solubility increases in the presence of lithium ions. It is present in mammals and plants. Polyglycine stretch associated with the chloroplast membrane protein, Toc5 is essential for envelop sorting.

Nota sulla preparazione

Prepared by phosphorylation.

Altre note

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Kiran Kumar Morishetti et al.
Journal of the American Society for Mass Spectrometry, 21(4), 603-614 (2010-01-29)
The sequence and conformational effects on the gas-phase acidities of peptides have been studied by using two pairs of isomeric cysteine-polyglycine peptides, CysGly(3,4)NH(2) and Gly(3,4)CysNH(2). The extended Cooks kinetic method was employed to determine the gas-phase acidities using a triple
Sergei Bykov et al.
The journal of physical chemistry. B, 114(19), 6636-6641 (2010-04-27)
Polyglycine (polygly) is an important model system for understanding the structural preferences of unfolded polypeptides in solution. We utilized UV resonance and visible Raman spectroscopy to investigate the conformational preferences of polygly peptides of different lengths in water containing LiCl
Solid-state 15 N NMR analysis of highly 15 N-enriched plant materials
Smernik RJ and Baldock JA
Plant and Soil, 275(1-2), 271-283 (2005)
Nicola J Rutherford et al.
Neurobiology of aging, 33(2), 424-424 (2010-11-16)
Insertion and deletion variants (indels) within poly glycine tracts of fused in sarcoma (FUS) were initially reported as causative of disease in amyotrophic lateral sclerosis (ALS). Subsequent studies identified similar indels in controls and suggested that these indels may confer
Dahiyana Cristancho et al.
The Journal of chemical physics, 132(6), 065102-065102 (2010-02-16)
Molecules that resemble a semiconductor diode depletion zone are those with an intrinsic electric dipole, which were suggested as potential electronic devices. However, so far, no single molecule has met such a goal because any electron donor-acceptor linker strongly diminishes
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Articoli

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Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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