P8047
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−R-Phycoerythrin antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Sinonimo/i:
Goat Anti-Human IgG
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About This Item
Origine biologica
goat
Coniugato
phycoerythrin (R-PE) conjugate
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
secondary antibodies
Clone
polyclonal
Forma fisica
buffered aqueous solution
tecniche
direct immunofluorescence: 1:32
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
modifica post-traduzionali bersaglio
unmodified
Descrizione generale
IgG is a glycoprotein antibody that contains two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4.
Immunogeno
Purified human IgG
Applicazioni
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment R-Phycoerythrin antibody produced in goat has been used in bead-based assay and immunoassay multiplex magpix
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment-R-Phycoerythrin antibody is suitable for use in flow cytometry . The antibody can also be used for direct immunofluorescence (1:32).
Azioni biochim/fisiol
Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising of one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallisable (fc), comprises the H chain constant region.
IgG antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders . The use of anti-human IgG (γ-chain specific), F(ab′)2 fragment-R-Phycoerythrin antibody helps avoid background staining due to the presence of Fc receptors. The product is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ, and Bence Jones λ myeloma proteins.
Stato fisico
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.1 mM EDTA, 1 mM iodoacetamide, 1% bovine serum albumin and 15 mM sodium azide
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
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PeerJ, 7, e6120-e6120 (2019-01-11)
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Anne E P Frosch et al.
The American journal of clinical nutrition, 100(3), 968-973 (2014-08-01)
Achieving optimal iron status in children in malaria-endemic areas may increase the risk of malaria. Malaria itself may contribute to iron deficiency, but the impact of an interruption in malaria transmission on the prevalence of iron deficiency is unknown. We
Bartholomew N Ondigo et al.
The Journal of infectious diseases, 210(7), 1123-1132 (2014-04-17)
Tools that estimate recent and long-term malaria transmission in a population would be highly useful for malaria elimination programs. The prevalence of antibodies to 11 Plasmodium falciparum antigens was assessed by cytometric bead assay or enzyme-linked immunosorbent assay in 1000
William Spooner et al.
Nature communications, 9(1), 4128-4128 (2018-10-10)
Selecting the most appropriate protein sequences is critical for precision drug design. Here we describe Haplosaurus, a bioinformatic tool for computation of protein haplotypes. Haplosaurus computes protein haplotypes from pre-existing chromosomally-phased genomic variation data. Integration into the Ensembl resource provides
Optimization of a magnetic bead-based assay MAGPIX textregistered-Luminex) for immune surveillance of exposure to malaria using multiple Plasmodium antigens and sera from different endemic settings
Varela ML, et al.
Malaria Journal, 17(1), 324-324 (2018)
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