P7412

Pirenzepine dihydrochloride

≥98% (TLC), powder

• Sinonimo/i: 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride
• Formula empirica (notazione di Hill): C₁₉H₂₁N₅O₂ · 2HCl
• Numero CAS: 29868-97-1
• Peso molecolare: 424.32
• Numero CE: 249-907-5
• Numero MDL: MFCD00055214
• Codice UNSPSC: 12352200
• ID PubChem: 24277863
• NACRES: NA.77

Proprietà

• Livello qualitativo: 200
• Saggio: ≥98% (TLC)
• Forma fisica: powder
• Colore: white
• Solubilità: H₂O: 50 mg/mL
• Stringa SMILE: Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24
• InChI: 1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H; FFNMBRCFFADNAO-UHFFFAOYSA-N
• Informazioni sul gene: human ... CHRM1(1128)

Descrizione

Descrizione generale

Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.

Applicazioni

Pirenzepine dihydrochloride has been used

• in transactivation of fibroblast growth factor receptor (FGFR).
• as a supplement in cell culture.
• for the stimulation of human fibroblasts

Azioni biochim/fisiol

Selective M₁ muscarinic acetylcholine receptor antagonist.

Caratteristiche e vantaggi

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Avvertenza

Hygroscopic; store desiccated at room temperature.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)