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P7181

Sigma-Aldrich

Polyethylene glycol solution

Hybri-Max, 50 % (w/v), average mol wt 1,450, 0.2 μm filtered, BioReagent, suitable for hybridoma

Sinonimo/i:

PEG Solution, Polyethylene Glycol

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About This Item

Numero MDL:
Codice UNSPSC:
12161902
ID PubChem:
NACRES:
NA.75

Grado

Hybri-Max

Livello qualitativo

Sterilità

0.2 μm filtered

Nome Commerciale

BioReagent

Stato

solution

PM

average mol wt 1,450

Concentrazione

50 % (w/v)

tecniche

cell culture | hybridoma: suitable

Impurezze

endotoxin, tested

Temperatura di conservazione

2-8°C

Stringa SMILE

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

Descrizione generale

Polyethylene glycol (PEG) is a polymer of ethylene oxide and water, obtained upon condensation.

Applicazioni

Polyethylene glycol solution has been used in the hybridization of the following:
  • irradiated camel fibroblast cells with A23 hamster cells
  • mouse splenocytes with Sp2/0-Ag 14 mouse myeloma cells
  • rabbit splenocytes and cell line 240E-1

Recommended for use in a normal fusion protocol requiring 50% PEG.

PEG is used as a fusogen to obtain hybridomas for monoclonal antibody production. Induces cell hybridization.

Azioni biochim/fisiol

Polyethylene glycol (PEG) is used in detergents, emulsifying agents, soaps, metal costing process, pharmaceutical preparations and cosmetics. PEG is commonly used as a lubricant. It′s application is also observed in chromatographic stationary phases. PEG prevents crystal formation in emulsions.

Confezionamento

Packaged in sealed ampules under nitrogen.

Altre note

Contains 50% (w/v) polyethylene glycol (Av. Mol. Wt. 1450) in DPBS without calcium.

Ricostituzione

Solution is ready-to-use. If a less concentrated solution is desired, dilute with sterile DPBS without calcium (D5773). Some precipitate may appear after being exposed to cooler, but should disappear as the solution warms. Solution may be frozen if desired but should first be aliquotted to avoid repeated freeze/thaw cycles.

Note legali

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

212.0 °F - closed cup

Punto d’infiammabilità (°C)

100 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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