P1306

Peptide YY human

≥97% (HPLC), synthetic

• Sinonimo/i: PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂
• Formula empirica (notazione di Hill): C₁₉₄H₂₉₅N₅₅O₅₇
• Numero CAS: 118997-30-1
• Peso molecolare: 4309.75
• Numero MDL: MFCD00081843
• Codice UNSPSC: 51111800
• NACRES: NA.32

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 200
• Saggio: ≥97% (HPLC)
• Stato: solid
• N° accesso UniProt: P10082
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... PYY(5697)

Descrizione

Amino Acid Sequence

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2

Descrizione generale

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

Applicazioni

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

Azioni biochim/fisiol

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

Inhibits secretin and cholecystokinin-stimulated pancreatic secretion;endogenous nonselective agonist at NPY receptors.

Altre note

Lyophilized from 0.1% TFA in H2O

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)