P0981
Anti-Potassium Channel TASK-1 antibody produced in rabbit
affinity isolated antibody, lyophilized powder
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About This Item
Coniugato:
unconjugated
application:
WB CL
Clone:
polyclonal
Reattività contro le specie:
human, rat
citations:
3
tecniche:
western blot (chemiluminescent): 1:200
Origine biologica
rabbit
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Stato
lyophilized powder
Reattività contro le specie
human, rat
tecniche
western blot (chemiluminescent): 1:200
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... KCNK3(3777)
mouse ... Kcnk3(16527)
rat ... Kcnk3(29553)
Categorie correlate
Immunogeno
synthetic peptide corresponding to amino acid residues 252-269 of human TASK-1 (with additional C-terminal cysteine). The epitope is highly conserved in mouse and rat TASK-1.
Stato fisico
Lyophilized at ~0.6 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Sven G Meuth et al.
The Journal of biological chemistry, 283(21), 14559-14570 (2008-04-01)
Two major K(+) channels are expressed in T cells, (i) the voltage-dependent K(V)1.3 channel and (ii) the Ca(2+)-activated K(+) channel KCa 3.1 (IKCa channel). Both critically influence T cell effector functions in vitro and animal models in vivo. Here we
F Duprat et al.
The EMBO journal, 16(17), 5464-5471 (1997-10-06)
TASK is a new member of the recently recognized TWIK K+ channel family. This 395 amino acid polypeptide has four transmembrane segments and two P domains. In adult human, TASK transcripts are found in pancreas<placenta<brain<lung, prostate<heart, kidney<uterus, small intestine and
Alexandra Mant et al.
Channels (Austin, Tex.), 7(4), 288-302 (2013-06-29)
Acid-sensitive, two-pore domain potassium channels, K(2P)3.1 and K(2P)9.1, are implicated in cardiac and nervous tissue responses to hormones, neurotransmitters and drugs. K(2P)3.1 and K(2P)9.1 leak potassium from the cell at rest and directly impact membrane potential. Hence altering channel number
Constanze Schmidt et al.
Circulation, 132(2), 82-92 (2015-05-09)
Antiarrhythmic management of atrial fibrillation (AF) remains a major clinical challenge. Mechanism-based approaches to AF therapy are sought to increase effectiveness and to provide individualized patient care. K(2P)3.1 (TASK-1 [tandem of P domains in a weak inward-rectifying K+ channel-related acid-sensitive
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