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Documenti fondamentali

P0916

Sigma-Aldrich

Anti-Pig IgG (whole molecule) antibody produced in rabbit

whole antiserum

Sinonimo/i:

Anti-Porcine IgG (whole molecule) antibody produced in rabbit, Anti-Swine IgG (whole molecule) antibody produced in rabbit

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

whole antiserum

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

contiene

15 mM sodium azide

tecniche

indirect ELISA: 1:40,000
quantitative precipitin assay: 2.8 mg/mL

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

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Descrizione generale

Immunoglobulin is a glycoprotein, with two heavy chain and two light chain connected by disulfide bond. IgG is a major class of immunoglobulin. IgG has five subclasses, such as- IgG1, IgG3, IgG2a and IgG2b.

Specificità

The antiserum is determined to be immunospecific for pig IgG.

Applicazioni

Anti-Pig IgG (whole molecule) antibody produced in rabbit has been used in enzyme linked immuno sorbent assay (ELISA) and quantitative precipitin assay.
Anti-Pig IgG (whole molecule) antibody produced in rabbit has been used in radial immunodiffusion and single radial immunodiffusion.

Azioni biochim/fisiol

IgG antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. It mainly helps in immune defense.

Stato fisico

Supplied as a liquid containing 15 mM sodium azide as preservative.

Nota sulla preparazione

treated to remove lipoproteins

Stoccaggio e stabilità

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Relationships between passive absorption of immunoglobulin G by the piglet and plasma concentrations of immunoglobulin G at weaning
Rooke JA, et al.
Livestock Production Science, 81(2), 223-234 (2003)
A Socha-Banasiak et al.
Journal of biological regulators and homeostatic agents, 31(1), 87-92 (2017-03-25)
Preterm human neonates, contrary to preterm piglets, obtain immunoglobulins from their mothers via the placenta during intrauterine development. However, one should note that the majority of trans-placental transfer of immunoglobulins in humans takes place during the last trimester of pregnancy.
Kateryna Goncharova et al.
PloS one, 12(6), e0180002-e0180002 (2017-06-29)
Neurological disorders are among the main clinical problems affecting preterm children and often result in the development of communication and learning disabilities later in life. Several factors are of importance for brain development, however the role of immunoglobulins (passive immunity
Kateryna Pierzynowska et al.
Journal of immunology research, 2020, 3813250-3813250 (2020-02-25)
The current study is aimed at highlighting the impact of enterally or parenterally applied immunoglobulins (Igs) on polyunsaturated fatty acid (PUFA) absorption in newborn pigs. Piglets were chosen as the appropriate model since they are born agammaglobulinemic and any effects
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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