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Merck
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Key Documents

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N7787

Sigma-Aldrich

NS3694

≥98%, powder

Sinonimo/i:

4-Chloro-2-[3-(3-trifluoromethyl-phenyl)-ureido]benzoic acid

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About This Item

Formula empirica (notazione di Hill):
C15H10ClF3N2O3
Numero CAS:
426834-38-0
Peso molecolare:
358.70
Numero MDL:
MFCD00249000
Codice UNSPSC:
12352200
ID PubChem:
24724557
NACRES:
NA.77

Saggio

≥98%

Forma fisica

powder

Solubilità

DMSO: soluble 22 mg/mL
H2O: insoluble <5 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F

InChI

1S/C15H10ClF3N2O3/c16-9-4-5-11(13(22)23)12(7-9)21-14(24)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H,22,23)(H2,20,21,24)
GNCZTZCPXFDPLI-UHFFFAOYSA-N

Informazioni sul gene

human ... GRIK1(2897)

Applicazioni

NS3694 may be used as an apoptosis inhibitor to study the relationship between the cellular mechanisms controlled by amputation-induced myeloid lineage activity.

Azioni biochim/fisiol

NS3694 can prevent the active apoptosome complex formation.
NS3694 is an Inhibitor of apoptosome formation.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Cindy X Kha et al.
Experimental eye research, 169, 38-47 (2018-01-23)
Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported
Developmental dependence for functional eye regrowth in Xenopus laevis.
Cindy X Kha et al.
Neural regeneration research, 13(10), 1735-1737 (2018-08-24)
Jovany J Franco et al.
Molecular biology of the cell, 30(16), 1890-1899 (2019-02-21)
Epithelial wound healing requires a complex orchestration of cellular rearrangements and movements to restore tissue architecture and function after injury. While it is well known that mechanical forces can affect tissue morphogenesis and patterning, how the biophysical cues generated after
Yantao Zhao et al.
Journal of agricultural and food chemistry, 67(46), 12761-12769 (2019-11-02)
There is convincing evidence that consuming whole grains (WGs) may decrease the risk of colorectal cancer (CRC). Wheat bran (WB) is a rich source of dietary fiber and phytochemicals with health-promoting properties. However, the active components especially the interaction between
Can Aztekin et al.
Development (Cambridge, England), 147(3) (2020-01-29)
Regeneration-competent vertebrates are considered to suppress inflammation faster than non-regenerating ones. Hence, understanding the cellular mechanisms affected by immune cells and inflammation can help develop strategies to promote tissue repair and regeneration. Here, we took advantage of naturally occurring tail
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