M2786
3-Maleimidobenzoic acid N-hydroxysuccinimide ester
crystalline
Sinonimo/i:
MBS
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About This Item
Formula empirica (notazione di Hill):
C15H10N2O6
Numero CAS:
Peso molecolare:
314.25
Beilstein:
1505254
Numero MDL:
Codice UNSPSC:
12352108
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Stato
crystalline
Livello qualitativo
Impiego in reazioni chimiche
reagent type: cross-linking reagent
Punto di fusione
175-177 °C (lit.)
Solubilità
DMSO: ≤20 mg/mL
Gruppo funzionale
NHS ester
maleimide
Temperatura di conservazione
−20°C
Stringa SMILE
O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O
InChI
1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
LLXVXPPXELIDGQ-UHFFFAOYSA-N
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Categorie correlate
Descrizione generale
may require addition of solvent to coupling buffer to at least 5% to maintain solubility
Applicazioni
3-Maleimidobenzoic acid N-hydroxysuccinimide ester (MBS) has been used as a protein cross-linker. It has been used for the stabilization of actin filaments in plant tissue samples.
3-Maleimidobenzoic acid N-hydroxysuccinimide ester has been used:
- in the fixation of pollen in Arabidopis
- as a component of Murashige and Skoog (MS) medium to stabilize F-actin in Eucalyptus root hairs
- in the fixation of F-actin labelled pollen tubes of Lilium davidii
Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.0, followed by coupling to compounds containing sulfhydryl by thioether at same pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Azioni biochim/fisiol
3-Maleimidobenzoic acid N-hydroxysuccinimide is used as a fixative for the preservation of pollen tube F-actin distribution. It imposes less damage when used on pollen tubes.
Altre note
The aryl maleimide is less stable than alkyl maleimide linkers.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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