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Key Documents

L0780

Sigma-Aldrich

Latex beads, amine-modified polystyrene, fluorescent blue

aqueous suspension, 0.05 μm mean particle size

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About This Item

Numero MDL:
Codice UNSPSC:
12352116
NACRES:
NA.56

Forma fisica

aqueous suspension

Livello qualitativo

Composizione

Solids, 2.5%

tecniche

cell based assay: suitable

Dimens. media particelle

0.05 μm

Fluorescenza

λex ~360 nm; λem ~420 nm

applicazioni

cell analysis

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Applicazioni

Latex beads, amine-modified polystyrene, fluorescent blue has been used:
  • to study its effects on the concentration-response relationship of bacterial cell viability
  • in the preparation of nanoparticles
  • as a model nanoparticle to study interactions with human blood and platelets

Azioni biochim/fisiol

Polystyrene latex beads can be used to create latex agglutination systems. Polystyrene latex beads have been used to study the transmission of Mycobacterium leprae, the causative pathogen of leprosy, as well as to develop a method for mass screening for both pulmonary and extrapulmonary tuberculosis.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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J-M Gineste et al.
Journal of microscopy, 243(2), 172-178 (2011-03-08)
The forward scattering of light in a conventional inverted optical microscope by nanoparticles ranging in diameter from 10 to 50nm has been used to automatically and quantitatively identify and track their location in three-dimensions with a temporal resolution of 200ms.
Optical signatures of small nanoparticles in a conventional microscope.
Eann A Patterson et al.
Small (Weinheim an der Bergstrasse, Germany), 4(10), 1703-1706 (2008-09-10)
INDUCTION OF EPIGENETIC RESPONSE TO AMINO-MODIFIED POLYSTYRENE NANOPARTICLES IN HUMAN CELLS
Koprinarova M, et al.
Comparative clinical pathology, 71(10) (2018)
Catherine McGuinnes et al.
Toxicological sciences : an official journal of the Society of Toxicology, 119(2), 359-368 (2010-12-03)
There is evidence that nanoparticles (NP) can enter the bloodstream following deposition in the lungs, where they may interact with platelets. Polystyrene latex nanoparticles (PLNP) of the same size but with different surface charge-unmodified (umPLNP), aminated (aPLNP), and carboxylated (cPLNP)-were
J Geys et al.
Toxicology letters, 160(3), 218-226 (2005-09-03)
Recent studies indicate that inhaled ultrafine particles can pass into the circulation. To study this translocation in an in vitro model three types of pulmonary epithelial cells were examined. The integrity of the cell monolayer was verified by measuring the

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