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H1635

Sigma-Aldrich

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

Sinonimo/i:

N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

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About This Item

Formula empirica (notazione di Hill):
C21H27N5O5 · xH2O
Numero CAS:
207386-83-2
Peso molecolare:
429.47 (anhydrous basis)
Beilstein:
5664178
Numero CE:
250-597-9
Numero MDL:
MFCD00149318
Codice UNSPSC:
12352204
ID PubChem:
24895469
NACRES:
NA.32

Nome del prodotto

N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)

Saggio

≥98% (HPLC)

Stato

powder

Colore

white to off-white

Solubilità

acetic acid: ~50 mg/mL

Temperatura di conservazione

−20°C

Stringa SMILE

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1
NWOJMNXIJBZMPK-QJHJCNPRSA-N

Informazioni sul gene

human ... ACE(1636) , ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421) , ACE2(70008) , ACE3(498012)

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Categorie correlate

Amino Acid Sequence

NBz-Gly-His-Leu

Applicazioni

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

Azioni biochim/fisiol

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

Substrati

Substrate for angiotensin converting enzyme.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLCG7087
SLBW5368
SLBR2049V
SLBK2049V
118K5006V

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