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Documenti fondamentali

GW20009F

Sigma-Aldrich

Anti-Transferrin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-Serotransferrin, Anti-Siderophilin

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

chicken

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

Reattività contro le specie

mouse, human, rat

Produttore/marchio commerciale

Genway 15-288-20009F

tecniche

indirect ELISA: suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... TF(7018)

Immunogeno

Immunogen Sequence: GI # 4557871, sequence 1-698
Serotransferrin native protein.

Applicazioni

Anti-Transferrin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also used for indirect ELISA.

Azioni biochim/fisiol

Transferrin is a glycoprotein that binds to and transports Fe3+ ions from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. It may also stimulate cell proliferation by supplying iron during DNA synthesis. Abnormal synthesis of transferrin may lead to accumulation of iron and microcytic hypochromic anemia.

Stato fisico

Solution in phosphate buffered saline containing 0.02% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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H A Huebers et al.
Blood, 61(2), 283-290 (1983-02-01)
A mechanism is proposed by which apotransferrin is secreted from mucosal cells, loaded with iron in the intestinal lumen, and then the intact complex is taken into the cell. Within the cell, iron is released and transferred to the blood
The role of transferrin in the mechanism of cellular iron uptake.
K Thorstensen et al.
The Biochemical journal, 271(1), 1-9 (1990-10-01)
E D Letendre et al.
Infection and immunity, 44(2), 320-325 (1984-05-01)
Hypoferremia, the reduction of plasma transferrin iron levels during infection, has been shown to control Neisseria meningitidis infection in mice. The exact nature of the mechanism that regulates this response has been obscure. We have previously shown that hypoferremia does
J Laskey et al.
Experimental cell research, 176(1), 87-95 (1988-05-01)
Transferrin is essential for cell proliferation and it was suggested that it may trigger a proliferative response following its interaction with receptors, serving as a growth factor. However, since the only clearly defined function of transferrin is iron transport, it
Jérôme Clatot et al.
Nature communications, 8(1), 2077-2077 (2017-12-14)
Fast opening and closing of voltage-gated sodium channels are crucial for proper propagation of the action potential through excitable tissues. Unlike potassium channels, sodium channel α-subunits are believed to form functional monomers. Yet, an increasing body of literature shows inconsistency

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