G21110-HH

DMT-2′O-Methyl-rG(ib) Phosphoramidite

• Sinonimo/i: DMT-2′-O-Me-rG(ib) amidite, N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-guanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Formula empirica (notazione di Hill): C₄₅H₅₆N₇O₉P
• Numero CAS: 150780-67-9
• Peso molecolare: 869.94
• Numero MDL: MFCD00792625
• Codice UNSPSC: 12352200
• ID PubChem: 329799863

Proprietà

• Origine biologica: non-animal source (no BSE/TSE risk)
• Livello qualitativo: 300
• Nome Commerciale: Proligo Reagents
• Saggio: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• Forma fisica: powder
• Confezionamento: pkg of 1 × 100 g (G211111-01); pkg of 1 × 500 g G211151-01
• tecniche: oligo synthesis: suitable
• Impurezze: ≤0.1% single unspecified Impurity (reversed phase HPLC); ≤0.3% mG2 (reversed phase HPLC, Hydrolysate); ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me); ≤0.3 wt. % water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT); ≤3 wt. % residual Solvent content
• Colore: white to off-white
• λ: conforms (UV/VIS Identity)
• Compatibilità: conforms to structure for H-NMR; conforms to structure for LC-MS
• Profilo del nucleoside: base: guanosine; base protecting group: isobutyryl; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: standard
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6C(=O)NC(NC(=O)C(C)C)=Nc56
• InChI: 1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1; IRRDHRZUOZNWDJ-MLLDKZSOSA-N

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)