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G0902

Sigma-Aldrich

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

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About This Item

Formula empirica (notazione di Hill):
C53H90O22
Numero CAS:
11021-14-0
Peso molecolare:
1079.27
Numero CE:
234-253-5
Numero MDL:
MFCD00133368
Codice UNSPSC:
12352201
ID PubChem:
24895029
NACRES:
NA.25

Origine biologica

plant root (Panax ginseng)

Livello qualitativo

200

Saggio

≥98% (HPLC)

Stato

powder

tecniche

HPLC: suitable

Temperatura di conservazione

2-8°C

Stringa SMILE

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3
JDCPEKQWFDWQLI-UHFFFAOYSA-N

Azioni biochim/fisiol

Ginsenoside-Rc exhibits anti-proliferative effects on human breast cancer cell lines and can induce expreβion of the leucine-zipper transcription factor c-fos.
Triterpene saponin found in ginseng.

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
087M4122V
047M4067V
14181025
016M4035V
084M4055V

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Sigma-Aldrich

G7253

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Ginsenoside Rg3 ≥98% (HPLC)

Sigma-Aldrich

SML0184

Ginsenoside Rg3

Ginsenoside Re primary reference standard

03000590

Ginsenoside Re

Ginsenoside Compound K ≥96% (HPLC)

Sigma-Aldrich

SMB00348

Ginsenoside Compound K

Ginsenoside Rb1 European Pharmacopoeia (EP) Reference Standard

Y0001347

Ginsenoside Rb1

vibrant-m

05115001

Panax ginseng extract

Louis Y Chan et al.
Reproductive toxicology (Elmsford, N.Y.), 19(1), 131-134 (2004-09-01)
Pregnant women commonly consume ginseng. However, there is little data concerning the effects of ginseng on early pregnancy. Rat embryos were exposed in vitro to different concentrations of Rc and Re from day 9.5 to day 11.5 after conception. Embryos
Myoung-Su Lee et al.
Journal of ethnopharmacology, 127(3), 771-776 (2009-12-08)
Panax ginseng and its major component, ginsenosides, are widely used for the prevention of various disorders in oriental medicine. To evaluate the effect of ginsenoside Rc (Rc), one of the active constituents in Panax ginseng, on glucose uptake in C2C12
Ron Luchtefeld et al.
Journal of agricultural and food chemistry, 52(16), 4953-4956 (2004-08-05)
A method based on high-performance liquid chromatography (HPLC) and negative ion electrospray mass spectrometry (LC-MS) has been used to determine ginsenosides Rb1, Rc, and Re in six different samples of ginseng. These included a liquid extract, capsules, tea bags, and
T B Ng et al.
Journal of ethnopharmacology, 16(2-3), 191-199 (1986-06-01)
Ginsenosides Rb2, Rc and Rg1 suppressed corticotropin-induced, dibutyryl cyclic AMP-induced and epinephrine-induced lipolysis with the relative potencies Rb2 greater than Rc greater than Rg1. The inhibition of corticotropin-induced lipolysis by ginsenoside Rg1 could not be overcome by increasing the dose
Young Joo Lee et al.
Archives of pharmacal research, 26(1), 53-57 (2003-02-06)
We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the control of AP-1/TPA response elements. We
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Chromatograms

application for HPLC

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