G0424

Corilagin

• Formula empirica (notazione di Hill): C₂₇H₂₂O₁₈
• Numero CAS: 23094-69-1
• Peso molecolare: 634.45
• Numero MDL: MFCD00238565
• Codice UNSPSC: 12352205
• ID PubChem: 329799812
• NACRES: NA.25

Proprietà

• Saggio: ≥98% (HPLC)
• Livello qualitativo: 200
• Stato: powder
• Solubilità: H₂O: 1 mg/mL, clear, colorless
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O[C@@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c(O)cc4C(=O)O[C@@H]1[C@@H](O)[C@@H](O2)OC(=O)c5cc(O)c(O)c(O)c5
• InChI: 1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1; TUSDEZXZIZRFGC-XIGLUPEJSA-N

Descrizione

Descrizione generale

Corilagin is a polyphenolic tannic acid and a major bioactive compound present in various plant species. It is an active component of Phyllanthus urinaria and Terminalia catappa L extract used to treat various ailments.

Applicazioni

Corilagin has been used to study its inhibitory effect on the growth of breast cancer by inducing apoptosis and autophagy regulated by the release of reactive oxygen species.

Azioni biochim/fisiol

Corilagin is a polyphenol, specifically a hydrolyzable tannin, found in Traditional Chinese Medicine herbal preparations. It is reported to have anti-inflammatory and anti-tumor activities.

Corilagin shows a variety of biological activities such as anti-inflammatory, anti-viral, anti-oxidant, hepatoprotective, antibacterial, anti-coagulant, hypolipemic and hypotensive. It has been noted to possess anti-tumor, antiproliferative, apoptotic, and autophagic abilities as well. Corilagin has been found to reduce the minimum inhibitory concentration (MIC) of β-lactams against Methicillin-resistant Staphylococcus aureus (MRSA).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable