E1235

EGF human

Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture

• Codice UNSPSC: 12352202

Proprietà

• Livello qualitativo: 300
• Stato: lyophilized powder
• PM: 7.3 kDa
• tecniche: cell culture | mammalian: suitable
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: -10 to -25°C

Descrizione

Descrizione generale

Recombinant human Epidermal Growth Factor is small polypeptide of 6.2 kDa protein containing 53 amino acid residues. The EGF gene encodes for a large type I membrane–anchored precursor protein which is cleaved into pro-EGF for generation of peptide hormone EGF. EGF can be found in human platelets, macrophages, urine, saliva, milk, and plasma.

Azioni biochim/fisiol

Epidermal Growth Factor (EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Biological activities ascribed to EGF include epithelial development, angiogenesis, inhibition of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture.

Nota sulla preparazione

For reconstitution: Briefly centrifuge the vial before opening. Reconstitute in water to a concentration of 0.1 mg/mL. Do not vortex. This solution is recommended to store in working aliquots at –20 oC to -80 oC. Store the lyophilized product at –20 oC. The product is stable for at least 2 years as supplied.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2